Background and Objective:
Healthcare associated infections (HAI) pose a serious threat to public health. The HAI are closely related to antimicrobial resistance (AMR). In 2018 a prevalence study by Suetens et al. coordinated at European level by the ECDC, estimated that 3.8 million patients acquire a HAI each year in Europe, confirming that such infections represent a significant health problem. The consequences that HAI and AMR have on public health can and must be contained with prevention and control actions. In the context of HAI the Surgical Site Infections (SSI) represent one of the most common adverse events occurring in surgical patients. The aim of study is to evaluate the main species involved in SSI and the postoperative antibiotics therapy.

Methods:
This is a retrospective study conducted in a.o.u. San giovanni e ruggi d’aragona hospitals in salerno, from january 2017 to december 2019. All patients who developed wound infection were included in the study. Incidence and common microorganisms of infection were identified. The identification and antibiotic sensitivity tests were performed with vitek 2. The ibm statistical package for social sciences version 22.00 (spss inc., chicago, il, usa) was used for data analysis.

Results:
A total of 82 patients were included in study group. The most common microorganisms isolated were gram-positive (53%) followed by gram-negative (39%) and fungi (8%). _enterococcus _spp (30.6%) and _staphylococcus_ spp (23.5%) were the main isolated among gram-positive. _staphyolococcus_ methicillin-resistant were 45%, and only 1% of _enterococcus_ spp were vancomicyn resistance.⟟ escherichia coli _(13%) and _klebsiella pneumoniae_ (9%) were the most isolated among gram-negative, of these only 35% of isolates were multidrug resistant.

Conclusion:
These results may help to the choice of empiric therapy and the antimicrobial prophylaxis strategies in ssi.