Background: Diabetes continues to rise globally. The disease brings patients, their families, and healthcare systems significant financial losses, including decreased productivity and burden economies. In 2021, diabetes affected approximately 537 million adults between the ages 20-79 years worldwide. Similar to Diabetes, prediabetes worldwide prevalence is rising, and it is estimated that by 2030 more than 470 million individuals will be prediabetic. Objective: To determine the association between risk for prediabetes and type 2 diabetes mellitus prevention practices among King Faisal University faculty members and administrative staff. Methods: An analytic cross-sectional study design was utilized. The prediabetes risk of respondents was assessed using a risk test which was developed, and validated by the CDC. However, participants prevention practices were determined using a researcher-developed questionnaire. The questionnaire was distributed to 360 selected faculty and administrative staff at three randomly selected health and three non-health colleges at King Faisal University, Al-Ahsa, Saudi Arabia. Data was subjected to estimation of proportion and logistic regression analyses using EpiInfo version 7. Results: Nearly 40% of respondents (39.72%, 95% C.I: 34.80, 44.86) were regarded as at high risk for prediabetes. Majority of respondents were consistent in practicing T2DM preventive measures related to processed food, smoking, and regular checking of weight and nutritional value of food. However, there was poor prevention in terms of exercise, consumption of sweetened beverages, and stress. When holding other variables constant, those who had high prediabetes risk were 19% less likely to engage in T2DM prevention. Conclusions: Five out of every 10 male respondents were classified as having high prediabetes risk. On the other hand, about two out of every 10 females had high prediabetes risk. Not all T2DM prevention aspects were consistently followed by the participants. Faculty and administrative staff who were at risk for prediabetes were not consistently practicing T2DM prevention.