The PHIRI project for measuring the impact of health crises on the European Healthcare System: the Italian case in COVID-19 pandemic
 
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1
Center of Epidemiology, Biostatistics and Medical Information Technology, Marche Polytechnic University, Italy
 
2
Department of Cardiovascular, Endocrine-metabolic Diseases and Aging, Istituto Superiore di Sanità-ISS, Rome, Italy
 
3
Department of Epidemiology and Health Reporting, Robert Koch Institute-RKI, Berlin, Germany
 
4
Swansea University Medical School, Swansea University, Swansea, United Kingdom
 
5
Data Science for Health Services and Policy Research Group, Institute for Health Sciences-IACS, Zaragoza, Spain
 
6
Austrian National Public Health Institute-GöG, Vienna, Austria
 
 
Publication date: 2023-04-26
 
 
Popul. Med. 2023;5(Supplement):A410
 
ABSTRACT
Background and Objective:
The CoViD-19 pandemic brought out the need for a uniform European response to public health issues. With the purpose of assessing the impact of the pandemic on European Healthcare Systems, the European project Population Health Information Research Infrastructure-PHIRI (EC H2020-IBA-INFRA-CORONA-2020 n. 101018317), aims to create and implement a federated research infrastructure based on the secondary use of administrative health-care databases data and real-world data. First Italian results from the Istituto Superiore di Sanità-ISS and the Polytechnic University of Marche-UNIVPM are reported.

Methods:
Four Use Cases (UC) were investigated. UC-A: Direct and indirect determinants of CoViD-19 infection on hospitalization of fragile populations (including heart attack and stroke (CVD), trauma, and hip and knee replacement surgery); UC-B: Delays in the treatment of breast cancer due to the pandemic; UC-C: Impact of CoViD-19 on perinatal health; UC-D: Changes in mental health status related to the CoViD-19 pandemic. PHIRI Research Centers developed and mutually shared the methodology, identified and processed the data necessary for the comparison between the pre (2017-19) and post (2020) pandemic periods using a Linux container (Docker). Docker allows sharing the analysis procedure, to perform it locally without any transfer of sensitive data, to produce structured results reports.

Results:
In UC-A (ISS), 1,088,026 hospitalizations were identified in Italy in 2017-2019 (451,015 for CVD; 400,057 for prosthetic surgery; 236,954 for trauma) and 338,740 in 2020 (140,421; 117,483; 80,836, respectively). In UC-B (UNIVPM), 818 new breast cancer interventions were identified in the Marche region in 2020; 2,964 in 2017-2019. Median time from diagnosis to surgery in 2020 was 39 days (1st-3rd Q: 26-61), 39 days (1st -3rd Q: 24-56) in 2017-2019 (p =0.08).

Conclusions:
Administrative health databases and real-world data in a federated research infrastructure can help European stakeholders to support shared decision-making in health crises.

ISSN:2654-1459
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