Background: Dengue is an arbovirosis, caused by infection of a virus of the genus Flavivirus, which is transmitted by females of two species of mosquitoes Aedes aegypti or Aedes albopictus, the latter less common in the national territory. It is noted that dengue is prevalent in the Brazilian territory, being endemic in the city of Araras. Objective: To trace the epidemiological profile of dengue in the municipality of Araras/São Paulo/Brazil between 2010 and 2021. Methodology: This is a cross-sectional, quantitative, retrospective, descriptive study based on public domain data extracted from the Notification Aggravation Information System (SINAN) linked to the Department of Informatics of the Single Health System (DATASUS). The cases were selected by the IDAGRAVO with the CID10 A90 (dengue), excluding other aggravations. The period covered was between 2010 and 2021 in the municipality of Araras, interior of the State of São Paulo/Brazil results: In the period studied, 12,006 cases of dengue were reported, the majority being female (55.7%), of white race (82.3%), with full middle education (32.37%). The majority of cases were of classical dengue (42.1%) diagnosed by clinical-epidemiological method evolving to cure (97.6%), and the most prevalent serotype is Dengue 1 (DENV 1) with notification of only 0.1%, most cases are still unknown. Conclusions: It is noted that dengue is still prevalent in the municipality of Araras, the subnotification and incorrect completion of the notification form present a challenge to the fight and characterization of the disease.