Association between glycemic levels and a frailty syndrome in the elderly of the longitudinal study of adult health (elsa-brasil)
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National School of Public Health, Oswaldo Cruz Foundation Brazil
Laboratory of Health and Environmental Education, Oswaldo Cruz Foundation, Brazil
Federal University of Minas Gerais Brazil
Publication date: 2023-04-26
Popul. Med. 2023;5(Supplement):A85
Some studies have reported the relationship between Frailty Syndrome and Diabetes Mellitus (DM), however, there is a lack of studies exploring the relationship between frailty and HbA1c. Thus, the objective of this article was to analyze the association between the of glycemic levels in around 10 years of follow-up and the prevalence of the frailty syndrome. Data are from the Longitudinal Study of Adult Health (ELSA-Brasil), a multicenter cohort of Brazilian civil servants. Frailty phenotype was defined with five criteria: fatigue, low physical activity, unintentional weight loss, slow walking speed and low handgrip strength. The presence of one or two of these criteria indicated a pre-frailty condition, and the presence of three or more indicated a frailty condition. The glycemic levels clusters had its defined through cluster analysis considering the HbA1c measurements in the three waves of the study: baseline: 2008-2010; wave 2 (2012-2014) e wave 3 (2017-2019). Data from 4,649 participants aged > 60 years were included. From the cluster analysis, 4 clusters of glycemic levels were identified (HbA1c 5.4% and 6.6% and 8.9%). Associations were estimated using multinomial regression models (crude and adjusted for sociodemographic variables and for hypertension). Compared to the elderly classified in the “HbA1c
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