Patient beliefs and experiences of adhering to medical therapies for cardiovascular comorbidities, before non-cardiac elective surgery in South Africa: a mixed-methods study
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1
School of Medicine, University of Leeds, Leeds, United Kingdom
2
Leeds Institute of Health research, University of Leeds, Leeds, United Kingdom
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Department of Anaesthesia and perioperative medicine, Groote Schuur Hospital, Cape Town, South Africa
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Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
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Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom
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Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
Popul. Med. 2026;8(Supplement Supplement 1):
ABSTRACT
INTRODUCTION:
Cardiovascular comorbidities increase perioperative risk in patients undergoing non-cardiac surgery. Optimizing medication adherence in this population is critical; yet adherence remains low in many low- and middle-income countries (LMICs), where health beliefs, systemic barriers, and healthcare communication bring significant challenges. This study aimed to explore the acceptability of validated patient-reported questionnaires and to investigate the beliefs and experiences influencing adherence to cardiovascular medication prior to surgery in a South African tertiary hospital.
METHODS:
A mixed-methods study was conducted using semi-structured interviews with 21 patients taking cardiovascular medication prior to vascular surgery. Participants completed four validated self-report questionnaires: Brief Illness Perception Questionnaire (BIPQ), Beliefs about Medicines Questionnaire (BMQ), SHARED decision-making questionnaire, and SURE decisional conflict scale. Questionnaire responses were summarized with descriptive statistics. Thematic analysis of interview data was conducted using Braun and Clarke’s six-step framework.
RESULTS:
Most participants perceived their illness as chronic (71%) and their treatment as effective (86%), yet 71% reported high concern and 43% reported emotional distress. Belief in the need for medication was strong (100%), but 67% worried about long-term side effects and 47% described their medication as a "mystery." Shared decision-making appeared limited: only 33% recalled being asked for their views. Thematic analysis revealed seven major themes: understanding illness and treatment, health professional interactions, service access, social support, individual factors, routines/habits.
CONCLUSIONS:
Patient-reported tools were acceptable and highlighted complex, interrelated factors associated with adherence. Integrating these tools into preoperative care may help identify at-risk patients and support person-centered perioperative planning in LMICs.