INTRODUCTION:
Transgender people experience significant inequities in access to and quality of health care, often associated with prejudicial attitudes held by health professionals. These attitudes may be expressed through stigmatization, discrimination, invisibilization, and disrespect for gender identity, undermining the therapeutic relationship, continuity of care, and health outcomes (1,2).

OBJECTIVE:
To map prejudicial attitudes of health professionals toward transgender people.

METHODS:
This literature review was conducted using scientific databases (CINAHL, PubMed, ERIC, Scopus, LILACS, and Web of Science Core Collection) and gray literature, with no temporal or language restrictions. Data were extracted using a structured instrument, considering the general characteristics of the studies and findings related to health professionals’ attitudes toward transgender people. The analysis was conducted descriptively.

RESULTS:
A total of 34 documents were identified, most of which were published in 2024 and conducted in the United States of America. The documents revealed a recurrent presence of prejudicial attitudes, manifested through discomfort during care, inappropriate use of chosen names and pronouns, cisnormative assumptions, pathologization of transgender identities, moral judgments, and denial or restriction of care. Attitudes based on conceptual misunderstandings about gender identity and on professionals’ personal, cultural, or religious beliefs were also identified.

CONCLUSIONS:
The evidence indicates that prejudicial attitudes among health professionals toward transgender people remain widespread and constitute a significant determinant of health inequities experienced by this population. Addressing this issue requires institutional anti-discrimination policies, continuous professional education, and the systematic integration of gender diversity as a core component of health education and practice, grounded in the principles of equity, human rights, and social justice.