ABSTRACT:
As new innovations and technologies for the biomanufacturing of new therapies and technologies emerge, Africa must be exposed to cutting-edge technologies that will shape the future of the sector. By cataloguing and analysing the existing emerging technologies being deployed in the advanced countries' biomanufacturing sectors, this review will clarify the basic principles of these innovations and examine their application in Africa. This provides a framework for African countries that are planning to develop or establish biomanufacturing capacities. The review focuses on the key technology areas related to infrastructure, design and development, providing a detailed analysis of these technologies, their implementation strategies and reference to organisations already using them. It provides insight into the operational principles of each technology and discusses their relevance and adaptation to the African context. The study also assesses the economic, social and political impacts of the adoption of these innovations, while also addressing potential challenges and constraints in the African context. Integrating these state-of-the-art technologies has the potential to improve product quality, operational efficiency, scalability and access to life-critical biopharmaceuticals. The analysis highlights current gaps in technology uptake in Africa's research and manufacturing sectors and provides targeted recommendations to policy makers, researchers and industry stakeholders to help boost competitiveness. Ultimately, strategic deployment of these innovations could strengthen healthcare systems, drive sustainable economic growth, and position Africa as a competitive player in the global biomanufacturing arena. At the domestic level, African countries therefore not only need to build productive capabilities, they also need to build governance capabilities and investment mechanisms that enable them to design and implement appropriate policies for dynamic structural transformation