Substance use and mental health disorders comorbidity among young and older adolescents: evidence from a secondary analysis of a large cross-sectional survey in Tanzania, East Africa
 
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School of Public Health, University of Cape Town, Cape town, South Africa
 
 
Popul. Med. 2026;8(Supplement Supplement 1):A2556
 
ABSTRACT
INTRODUCTION:
Co-morbidity between substance use and mental health disorders among adolescents is a growing global public health concern, associated with poorer clinical and social outcomes (1,2). Adolescence is a critical developmental period marked by biological and social changes that increase vulnerability to both conditions and their co-occurrence (1,3,4). Evidence from Sub-Saharan Africa, including Tanzania, remains limited, as most studies examine the disorders separately (5,6-8). This study aims to determine the prevalence and determinants of substance use and mental health disorder co-morbidity among adolescents aged 10–19 years in the Tanga region, Tanzania, using secondary analysis of a large cross-sectional survey.

METHODS:
This cross-sectional analytical study uses secondary data from a population-based survey conducted in 2021 by the Africa Academy for Public Health (AAPH)(6). The analysis includes in-school and out-of-school adolescents aged 10–19 years. Co-morbidity is defined as concurrent substance use in the past 30 days preceding the primary survey (cigarettes, tobacco, alcohol, marijuana, or other illicit drugs) and a mental health disorder (depression and/or suicide risk). Depression is defined as a Patient Health Questionnaire (PHQ-9) score ≥5, while suicide risk is based on suicidal ideation in the past month preceding the survey or a lifetime history of attempt. Exposures include sociodemographic characteristics, employment history, mobile phone ownership, social media use, parental survival status, sexual history, and self-reported HIV status. Descriptive statistics are used to estimate prevalence, and chi-square tests and multivariable logistic regression models are used to identify determinants.

RESULTS:
The dataset included 1,262 adolescents, of whom 1,031 were in school, and 231 were out of school. Data analysis is ongoing.

CONCLUSIONS:
Substance use and mental health disorder co-morbidity is a major concern among adolescents. Findings from this study will enhance understanding of this co-morbidity among Tanzanian adolescents and inform interventions and policies addressing both conditions in Tanzania and across Africa.
eISSN:2654-1459
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