Recent Articles
Archive of Issues
Aim and Scope
Editorial Board
Open Access
Indexing
Why publish with us
Contact Us
Instructions to Authors (PDF)
Manuscript Types
Manuscript Formatting
How to submit
Special publications & Reprints
Preprints
Authorship & COI
Principles of Transparency Checklist
Publication Ethics and Publication Malpractice Statement
Crossmark
Data Policies
Supporting Diversity
The characteristics and outcomes of COVID-19 positive Haematology patients at a Tertiary Hospital in Western Cape South Africa
1
University of Cape Town Barnard Fuller Building, Anzio Rd, Observatory, Cape Town, 7935 South Africa
2
University of Cape Town The characteristics and outcomes of COVID-19 positive Haematology patients at a Tertiary Hospital in Western Cape South Africa South Africa
3
University of Cape Town
4
Universisty of Cape Town Barnard Fuller Building, Anzio Rd, Observatory, Cape Town, 7935 South Africa
Publication date: 2023-04-26
Popul. Med. 2023;5(Supplement):A1504
ABSTRACT
Introduction:
Patients with haematological diseases, commonly have lasting immunodeficiency due to their disease or related treatments. Research suggests that COVID-19 positive patients with haematological diseases have worse outcomes than non-haematological patients however, there is limited data from Africa and South Africa.
Methods:
A retrospective review of all COVID-19 positive patients with an existing Haematology diagnosis from January 2020 to April 2021 (encompassing two waves of COVID-19), at Groote Schuur Hospital. Descriptive and inferential statistics to evaluate data.
Results:
A total of 53 patients with the haematological disease were identified(35 infected in the first wave and 18 in the second wave). Of these participants, 51% were male with a median age of 47.5 years (IQR:35.6-60.3); half were because of severe COVID-19 illness (47%), 28% were diagnosed during non-covid admission and 25% were outpatients. Lymphoma was the most common haematological diagnosis(45%), followed by those with cytopenias or myeloma/plasma cell disorders (each 13%). The majority of cases had more than one comorbidity (62%), were HIV negative (81%), were non-smokers (77%) and had an ECOG (Eastern Cooperative Oncology Group) score of 0 (40%).  The most commonly reported symptoms were shortness of breath (53%), cough (51%) and fever (38%) while 17% of patients reported no symptoms. Prior to COVID-19 infection, 40 patients (75%) had a survival prognosis of >12 months of whom 13% succumbed to COVID-19. Of the 13 patients (25%) with a survival prognosis of
Patients with haematological diseases, commonly have lasting immunodeficiency due to their disease or related treatments. Research suggests that COVID-19 positive patients with haematological diseases have worse outcomes than non-haematological patients however, there is limited data from Africa and South Africa.
Methods:
A retrospective review of all COVID-19 positive patients with an existing Haematology diagnosis from January 2020 to April 2021 (encompassing two waves of COVID-19), at Groote Schuur Hospital. Descriptive and inferential statistics to evaluate data.
Results:
A total of 53 patients with the haematological disease were identified(35 infected in the first wave and 18 in the second wave). Of these participants, 51% were male with a median age of 47.5 years (IQR:35.6-60.3); half were because of severe COVID-19 illness (47%), 28% were diagnosed during non-covid admission and 25% were outpatients. Lymphoma was the most common haematological diagnosis(45%), followed by those with cytopenias or myeloma/plasma cell disorders (each 13%). The majority of cases had more than one comorbidity (62%), were HIV negative (81%), were non-smokers (77%) and had an ECOG (Eastern Cooperative Oncology Group) score of 0 (40%).  The most commonly reported symptoms were shortness of breath (53%), cough (51%) and fever (38%) while 17% of patients reported no symptoms. Prior to COVID-19 infection, 40 patients (75%) had a survival prognosis of >12 months of whom 13% succumbed to COVID-19. Of the 13 patients (25%) with a survival prognosis of
| ISSN: | 2654-1459 |
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
