Barriers and facilitators to coverage of HIV prevention innovations among adolescent girls and young women (AGYW) in South Africa
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South African Medical Research Council. Health Systems Research Unit, South African Medical Research Council, Cape Town, South Africa
Popul. Med. 2026;8(Supplement Supplement 1):A2338
ABSTRACT
INTRODUCTION:
Adolescent girls and young women (AGYW) in South Africa are at high risk of HIV infection. AGYW experience barriers and facilitators to coverage of HIV prevention innovations.
METHODS:
We conducted a “post-intervention” household survey in 12 intervention subdistricts, and 12 comparison subdistricts with equivalent demographics and HIV prevalences, across 8 provinces in South Africa. Two sites were purposefully selected within each intervention and comparison area, generating 48 sites. In each site, we conducted a representative household survey of 100 AGYW aged 15-24 years, (N=4,800). Dried blood spot specimens were collected, and participants self-completed an electronic questionnaire. Frequencies and percentages for each outcome were presented for intervention and comparison arms. We described the barriers and facilitators associated with the coverage of HIV prevention innovations among AGYW using random effects logistic regression models. Univariate and multivariate analysis will be conducted.
RESULTS:
Overall, male or female condom use a 100% of the time when having sex in the past six months was reported by 15.0% in the intervention arm and 11.8% in the comparison arm. HIV testing in the past year overall was 69.4% in the intervention arm and 59.6% in the comparison arm (OR=1.65; 95% CI:1.16 - 2.35 p=0.0110), while the HIV self-testing was 13.6% in the intervention arm and 7.9% in the comparison arm. More participants (26.4%) in the intervention arm had ever used PrEP compared with 13.0% in the comparison arm (OR=2.19; 95% CI 1.11 - 4.30; p=0.0331). Recent or last HIV self-testing was higher in the intervention arm than in the comparison arm (13.7% versus 7.2%).
CONCLUSIONS:
These findings highlight the importance of interventions targeted at addressing barriers and facilitators to coverage of HIV prevention innovations among this priority population. Exploring barriers to coverage of HIV prevention innovations in-depth are required to generate robust research to expand coverage.